Manufacturing technology
Solid formulations:
Options for manufacturing:
- Mixing by use of a Turbula, High Sheer Mixer (Glatt) or Planet Mixer
- Blending of powder, granules or pellets
- Manufacturing of mixtures for direct compression
- Manufacturing of placebo mixtures
- Agglomeration/Granulation – Wet granulation –
– single pot: high sheer mixing by cooling or heating conditions (Glatt)
– Fluid bed system: wurster coating (bottom spray), top spray (Glatt) - Drying for granulation, layering and coating applications
- Pelletizing and development (Multiple Unit Pellet Systems, MUPS
- Compression (various punches are available)
- Filmcoating (tablet coating, sugar coating)
- Scale up and adjustment to GMP-condition
